Rabbit Polyclonal Antibody to CACNA1C
货号:
P11613
别名:
TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q13936
规格:
目录价
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Description |
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This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. |
Specification |
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Aliases | TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1 |
Swissprot | Q13936 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CACNA1C |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/1000-1/2000 |