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Mouse Monoclonal Antibody to PCNA
货号: 30453A
别名:
应用: WB,IHC,FCM
反应种属: Human,Mouse,Rat,Rabbit,Monkey
抗体类型: Loading Control Antibody
Swissprot: P12004
规格:
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Description

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

References

1.Cancer Res. 2012 Jul 1;72(13):3217-27.
2.PLoS One. 2012;7(1):e29416.

Specification

Entrez GeneID 5111
Swissprot P12004
clone 7H4F8
WB Predicted band size 28.7kDa
Host/Isotype Mouse IgG1
Antibody Type Loading Control Antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Rabbit,Monkey
Immunogen Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/100 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000
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