Rabbit Polyclonal Antibody to ESPL1
货号：
P11746
别名：
ESP1; SEPA
应用：
IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q14674
规格：
目录价
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Description |
|---|
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]). |
Specification |
|
|---|---|
| Aliases | ESP1; SEPA |
| Swissprot | Q14674 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ESPL1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/50-1/200 |
| ELISA | 1/2000-1/5000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P11746(ESPL1 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11746(ESPL1 Antibody) at dilution 1/40. (Original magnification: ×200)
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