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Rabbit Polyclonal Antibody to CASP8AP2
货号: P11766
别名: CED-4; FLASH; RIP25
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q9UKL3
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Description

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Specification

Aliases CED-4; FLASH; RIP25
Swissprot Q9UKL3
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human CASP8AP2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/25-1/100
ELISA 1/1000-1/2000
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