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Mouse Monoclonal Antibody to SPP1
货号: 30443
别名: OPN; BNSP; BSPI; ETA-1
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P10451
规格:
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Description

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.


References

1.Blood. 2012 May 31;119(22):5215-20.
2.J Cancer Res Ther. 2011 Apr-Jun;7(2):138-42.

Specification

Aliases OPN; BNSP; BSPI; ETA-1
Entrez GeneID 6696
Swissprot P10451
clone 7C5H12
WB Predicted band size 35.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200-1/400
ELISA 1/10000
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