产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Rabbit Polyclonal Antibody to IPO7
货号: P11857
别名: Imp7; RANBP7
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: O95373
规格:
目录价
在线咨询

Description

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Specification

Aliases Imp7; RANBP7
Swissprot O95373
WB Predicted band size 120 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human IPO7
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/100-1/300
ELISA 1/2000-1/5000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852