Mouse Monoclonal Antibody to TGFBR3
货号：
30449A
别名：
BGCAN; betaglycan
应用：
WB,FCM
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q03167
规格：
目录价
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Description |
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This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
References |
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| 1.Mol Biol Cell. 2011 May;22(9):1463-72. 2.Zhongguo Fei Ai Za Zhi. 2010 May;13(5):451-7. |
Specification |
|
|---|---|
| Aliases | BGCAN; betaglycan |
| Entrez GeneID | 7049 |
| Swissprot | Q03167 |
| clone | 1C5H11 |
| WB Predicted band size | 93.4kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using TGFBR3 mouse mAb against Jurkat (1), HeLa (2), MCF-7 (3), F9 (4), SK-N-SH (5), and NIH3T3 (6) cell lysate.
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Flow cytometric analysis of MOLT4 cells using TGFBR3 mouse mAb (green) and negative control (purple).
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