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Mouse Monoclonal Antibody to CBX8
货号: 30456A
别名: PC3; RC1
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9HC52
规格:
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Description

Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.

References

1.Cancer Cell. 2011 Nov 15;20(5):563-75.
2.EMBO J. 2007 Mar 21;26(6):1637-48.

Specification

Aliases PC3; RC1
Entrez GeneID 57332
Swissprot Q9HC52
clone 9C3D4
WB Predicted band size 43.4kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000
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