Mouse Monoclonal Antibody to CBX8
货号:
30456A
别名:
PC3; RC1
应用:
FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9HC52
规格:
目录价
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Description |
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Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus. |
References |
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1.Cancer Cell. 2011 Nov 15;20(5):563-75. 2.EMBO J. 2007 Mar 21;26(6):1637-48. |
Specification |
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Aliases | PC3; RC1 |
Entrez GeneID | 57332 |
Swissprot | Q9HC52 |
clone | 9C3D4 |
WB Predicted band size | 43.4kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |