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Rabbit Polyclonal Antibody to RCC1
货号: P12101
别名: CHC1; RCC1-I; SNHG3-RCC1
应用: WB
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P18754
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Description

RCC1 (regulator of chromosome condensation 1), increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor, deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex.

Specification

Aliases CHC1; RCC1-I; SNHG3-RCC1
Swissprot P18754
WB Predicted band size 44 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human RCC1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
ELISA 1/5000-1/10000
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