Mouse Monoclonal Antibody to DCTN4
货号:
30469P
别名:
P62; DYN4
应用:
WB,IHC,IF,FCM
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9UJW0
规格:
目录价
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Description |
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Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B. |
References |
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1.Cell. 2008 Dec 26;135(7):1189-200. 2.J Biol Chem. 2006 May 19;281(20):14006-14. |
Specification |
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Aliases | P62; DYN4 |
Entrez GeneID | 51164 |
Swissprot | Q9UJW0 |
clone | 3G9D7 |
WB Predicted band size | 52.3kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Western blot analysis using DCTN4 mouse mAb against Raw264.7 (1) and NIH3T3 (2) cell lysate.
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Immunofluorescence analysis of HepG2 cells using DCTN4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
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Flow cytometric analysis of A549 cells using DCTN4 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using DCTN4 mouse mAb with DAB staining.