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Mouse Monoclonal Antibody to DCTN4
货号: 30469P
别名: P62; DYN4
应用: WB,IHC,IF,FCM
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q9UJW0
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Description

Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.

References

1.Cell. 2008 Dec 26;135(7):1189-200.
2.J Biol Chem. 2006 May 19;281(20):14006-14.

Specification

Aliases P62; DYN4
Entrez GeneID 51164
Swissprot Q9UJW0
clone 3G9D7
WB Predicted band size 52.3kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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