Rabbit Polyclonal Antibody to SLC17A1
货号：
P12209
别名：
NPT1; NPT-1; NAPI-1
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q14916
规格：
目录价
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Description |
|---|
NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1å and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport. |
Specification |
|
|---|---|
| Aliases | NPT1; NPT-1; NAPI-1 |
| Swissprot | Q14916 |
| WB Predicted band size | 51 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human SLC17A1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/2000-1/5000 |
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