Mouse Monoclonal Antibody to PDE1B
货号：
30465A
别名：
PDE1B1; PDES1B
应用：
WB,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q01064
规格：
目录价
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Description |
|---|
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
References |
|---|
| 1.J Biol Chem. 2007 Nov 9;282(45):32749-57. 2.Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):497-502. |
Specification |
|
|---|---|
| Aliases | PDE1B1; PDES1B |
| Entrez GeneID | 5153 |
| Swissprot | Q01064 |
| clone | 10B10B12 |
| WB Predicted band size | 61.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using PDE1B mouse mAb against A549 (1), SK-MES-1 (2), PC-12 (3), NIH3T3 (4), and 3T3-L1 (5) cell lysate.
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Flow cytometric analysis of A549 cells using PDE1B mouse mAb (green) and negative control (red).
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