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Rabbit Polyclonal Antibody to SLC7A11
货号: P12430
别名: xCT; CCBR1
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q9UPY5
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Description

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Specification

Aliases xCT; CCBR1
Swissprot Q9UPY5
WB Predicted band size 55 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human SLC7A11
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/1000-1/5000
IHC 1/50-1/100
ELISA 1/5000-1/10000
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