Rabbit Polyclonal Antibody to XPC
货号:
P12435
别名:
XP3; RAD4; XPCC; p125
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q01831
规格:
目录价
在线咨询
Description |
---|
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |
Specification |
|
---|---|
Aliases | XP3; RAD4; XPCC; p125 |
Swissprot | Q01831 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human XPC |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
-
The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P12435(XPC Antibody) at dilution 1/20. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12435(XPC Antibody) at dilution 1/20. (Original magnification: ×200)