Rabbit Polyclonal Antibody to HDAC4
货号:
P12665
别名:
HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; NEDCHF; NEDCHID
应用:
IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P56524
规格:
目录价
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Description |
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. |
Specification |
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Aliases | HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; NEDCHF; NEDCHID |
Swissprot | P56524 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human HDAC4 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/50-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P12665(HDAC4 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12665(HDAC4 Antibody) at dilution 1/40. (Original magnification: ×200)