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Rabbit Polyclonal Antibody to CASP4
货号: P12853
别名: TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P49662
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Description

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Specification

Aliases TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
Swissprot P49662
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide of human CASP4
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/25-1/100
ELISA 1/5000-1/10000
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