Rabbit Polyclonal Antibody to CASP4
货号:
P12853
别名:
TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P49662
规格:
目录价
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Description |
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This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
Specification |
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Aliases | TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II |
Swissprot | P49662 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CASP4 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12853(CASP4 Antibody) at dilution 1/25. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12853(CASP4 Antibody) at dilution 1/25. (Original magnification: ×200)