Mouse Monoclonal Antibody to ITGA2B
货号：
30485P
别名：
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2
应用：
IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P08514
规格：
目录价
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Description |
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ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
References |
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| 1. Pediatr Blood Cancer. 2012 Aug;59(2):335-8. 2. Blood. 2011 Dec 1;118(23):5996-6005. |
Specification |
|
|---|---|
| Aliases | GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2 |
| Entrez GeneID | 3674 |
| Swissprot | P08514 |
| clone | 2E10C9 |
| WB Predicted band size | 113.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Flow cytometric analysis of HL60 cells using ITGA2B mouse mAb (green) and negative control (purple).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using ITGA2B mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using ITGA2B mouse mAb with DAB staining.
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