Rabbit Polyclonal Antibody to CD276
货号:
P13039
别名:
B7H3; B7-H3; B7RP-2; 4Ig-B7-H3
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q5ZPR3
规格:
目录价
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Description |
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The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Specification |
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Aliases | B7H3; B7-H3; B7RP-2; 4Ig-B7-H3 |
Swissprot | Q5ZPR3 |
WB Predicted band size | 57 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human CD276 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: PC-3, 231, LNCAP and 293T cell lysates, Primary antibody: P13039(CD276 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13039(CD276 Antibody) at dilution 1/20. (Original magnification: ×200)