Rabbit Polyclonal Antibody to CDC14B
货号:
P13046
别名:
CDC14B3; Cdc14B1; Cdc14B2; hCDC14B
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O60729
规格:
目录价
在线咨询
Description |
---|
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. |
Specification |
|
---|---|
Aliases | CDC14B3; Cdc14B1; Cdc14B2; hCDC14B |
Swissprot | O60729 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CDC14B |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |