Rabbit Polyclonal Antibody to CHM
货号:
P13077
别名:
TCD; GGTA; REP-1; DXS540; HSD-32
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P24386
规格:
目录价
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Description |
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This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. |
Specification |
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Aliases | TCD; GGTA; REP-1; DXS540; HSD-32 |
Swissprot | P24386 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CHM |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/50-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P13077(CHM Antibody) at dilution 1/85. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P13077(CHM Antibody) at dilution 1/85. (Original magnification: ×200)