Mouse Monoclonal Antibody to IL2RA
货号：
30522
别名：
CD25; IL2R; TCGFR; IDDM10
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Monkey,Rat
抗体类型：
Primary antibody
Swissprot：
P01589
规格：
目录价
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Description |
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The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
References |
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| 1. Ann Hematol. 2012 Oct;91(10):1597-602. 2. Transplant Proc. 2012 May;44(4):1139-42. |
Specification |
|
|---|---|
| Aliases | CD25; IL2R; TCGFR; IDDM10 |
| Entrez GeneID | 3559 |
| Swissprot | P01589 |
| clone | 1B5D12 |
| WB Predicted band size | 30.8kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Monkey,Rat |
| Immunogen | Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using IL2RA mouse mAb against Hela (1), MOLT4 (2), HEK293 (3), A549 (4), Jurkat (5), K562 (6), Cos7 (7), PC-12 (8) and NIH/3T3 (9) cell lysate.
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Immunofluorescence analysis of Hela cells using IL2RA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using IL2RA mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using IL2RA mouse mAb with DAB staining.
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