Rabbit Polyclonal Antibody to CCP110
货号：
P13213
别名：
CP110; Cep110
应用：
IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
O43303
规格：
目录价
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Description |
|---|
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). |
Specification |
|
|---|---|
| Aliases | CP110; Cep110 |
| Swissprot | O43303 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human CCP110 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/20-1/100 |
| ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P13213(CCP110 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13213(CCP110 Antibody) at dilution 1/20. (Original magnification: ×200)
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