Rabbit Polyclonal Antibody to CYP3A5
货号:
P13233
别名:
CP35; PCN3; CYPIIIA5; P450PCN3
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P20815
规格:
目录价
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Description |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. |
Specification |
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Aliases | CP35; PCN3; CYPIIIA5; P450PCN3 |
Swissprot | P20815 |
WB Predicted band size | 57 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CYP3A5 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HEPG2 cell lysate, Primary antibody: P13233(CYP3A5 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 7 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13233(CYP3A5 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P13233(CYP3A5 Antibody) at dilution 1/20. (Original magnification: ×200)