Rabbit Polyclonal Antibody to EIF2S1
货号：
P13304
别名：
EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P05198
规格：
目录价
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Description |
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The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). |
Specification |
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|---|---|
| Aliases | EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha |
| Swissprot | P05198 |
| WB Predicted band size | 36 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human EIF2S1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/30-1/150 |
| ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-6: A549 cell, Human placenta tissue, A172 cell, NIH/3T3 cell, Jurkat cell, Hela cell lysates, Primary antibody: P13304(EIF2S1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P13304(EIF2S1 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P13304(EIF2S1 Antibody) at dilution 1/20. (Original magnification: ×200)
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